Wow. Quite the discussion we’ve got going here.
Samus would win, of course!! SHE’D POWER-BEAM HIS ARMOR-PLATED ASS!!
is hit by a brick for spamming
AGH! Sorry… XD
Anyway, all silliness aside, I’d like to put in my opinion - in a moderate-range-starting-point (ten meters from each other in this case) encounter with Master Cheif equipped with a rocket launcher and SMG/other small-arms, and Samus from Metroid Prime equipped with the Varia Suit, Missile Launcher, Power Beam, and around 100 missiles… well, let’s just go over it.
If Master Cheif launches a rocket at Samus, Samus leaps out of the way (Both of them are from the video games - the rocket doesn’t move nearly as fast as it would in real life there). Samus fires a missile from that range, the Cheif leaps over it, as it’s fairly slow as well. Samus uses the power beam and Master Cheif’s shields might get knocked down, but he would probably launch a rocket then, forcing Samus to dodge, interrupting her fire and giving Cheif a chance to regain his shielding.
It all really comes down to wether Master Cheif can get her into short range - she wouldn’t stand a chance then. She wouldn’t be able to dodge his shots and he would be able to hit her with a melee attack. Her own suit doesn’t make her as strong as him, so she wouldn’t be able to defend herself hand-to-hand. Even just out of hand-to-hand range would work, though - he could still hit her reliably then. However, if she managed to stay out of range and keep pummelling him with the Power Beam, she could knock his shields down, dash forward while firing, and hit him with a missile/super missile before he could do anything.
Extreme-long-range (100 meters, again, in this case) with Master Cheif with the sniper rifle would probably result in a Cheif victory. Of course, Samus could always close the gap between them, making the sniper rifle less effective.
So, close range and long range, cheif victory, but at moderate range (at least under the parameters of my own little battle here), I say Samus. If Cheif could get her two feet away from him she wouldn’t stand a chance, but as long as she could keep her distance she’d wear him down.
In a realistic confrontation, I have no idea at all. I’ll leave that up to you experts 